منابع مشابه
Continuing controversy: pneumococcal vaccine and COPD.
E nthusiasm for pneumococcal vaccines has waxed and waned for decades, Although demonstrated effective among United States Army recruits in 1945,’ pneumococcal vaccines were little utilized in an era which saw mortality from bacteremic disease decrease from greater than 70 percent in the pre-penicillin era,2 to 15-45 percent in more recent literature.3 Recognition of this persistent mortality h...
متن کاملDosing Schedules for Pneumococcal Conjugate Vaccine
Since second generation pneumococcal conjugate vaccines (PCVs) targeting 10 and 13 serotypes became available in 2010, the number of national policy makers considering these vaccines has steadily increased. An important consideration for a national immunization program is the timing and number of doses-the schedule-that will best prevent disease in the population. Data on disease epidemiology a...
متن کاملThe pertussis vaccine controversy in Great Britain, 1974-1986.
This historical essay analyzes the role played by Great Britain in the pertussis vaccine controversy of the 1970s and 1980s. Public backlash against this vaccine not only took place earlier in Britain than the United States, but also was so widespread that a series of whooping cough epidemics soon followed. As with the more recent dispute involving measles-mumps-rubella (MMR) vaccine and autism...
متن کاملBudget constraint and vaccine dosing: a mathematical modelling exercise
BACKGROUND Increasing the number of vaccine doses may potentially improve overall efficacy. Decision-makers need information about choosing the most efficient dose schedule to maximise the total health gain of a population when operating under a constrained budget. The objective of this study is to identify the most efficient vaccine dosing schedule within a fixed vaccination budget from a heal...
متن کاملSystematic Review of the Effect of Pneumococcal Conjugate Vaccine Dosing Schedules on Vaccine-type Nasopharyngeal Carriage
BACKGROUND Pneumococcal conjugate vaccines (PCV) reduce nasopharyngeal carriage of vaccine type (VT) pneumococci, an important driver of vaccine programs' overall benefits. The dosing schedule that best reduces carriage is unclear. METHODS We performed a systematic review of English language publications from 1994 to 2010 (supplemented post hoc with studies from 2011) reporting PCV effects on...
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ژورنال
عنوان ژورنال: New Scientist
سال: 2021
ISSN: 0262-4079
DOI: 10.1016/s0262-4079(21)00033-6